The importance of vitamin C in the pathogenesis of arthrosclerosis and other forms of cardiovascular disease cannot be fully understood without reference to the following landmark paper published by
This is a must-read article for all interested to prevent or to reverse cardiovascular disease.
A
Unified Theory of Human Cardiovascular Disease Leading the Way to the Abolition
of This Disease as a Cause for Human Mortality This full article, along with many other features, are available FREE when you purchase:
Matthias Rath M.D. and Linus Pauling PhD
"An important scientific innovation rarely, makes its way by gradually winning
over and converting its opponents. What does happen is that its opponents
gradually die out and that the growing generation is familiar with the idea
from the beginning."
-Max Planck
This paper is dedicated to the young physicians and the medical students
of this world
Abstract
Until now therapeutic concepts for human cardiovascular disease (CVD) were
targeting individual pathomechanisms or specific risk factor. On the basis
of genetic, metabolic, evolutionary, and clinical evidence we present here
a unified pathogenetic and therapeutic approach. Ascorbate
deficiency is the precondition and common denominator of human CVD. Ascorbate
deficiency is the result of the inability of man to synthesize ascorbate
endogenously in combination with insufficient dietary intake. The invariable
morphological consequences of chronic ascorbate deficiency in the vascular
wall are the loosening of the connective tissue and the loss of the endothelial
barrier function. Thus human CVD
is a form of pre-scurvy. The multitude of pathomechanisms that
lead to the clinical manifestation of CVD are primarily defense mechanisms
aiming at the stabilization of the vascular wall. After the loss of endogenous
ascorbate production during the evolution of man these defense mechanisms
became life-saving. They counteracted the fatal consequences of scurvy and
particularly of blood loss through the scorbutic vascular wall. These countermeasures
constitute a genetic and a metabolic level. The genetic level is characterized
by the evolutionary advantage of inherited features that lead to a thickening
of the vascular wall, including a multitude of inherited diseases.
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