Beta-Sitosterol

Beta-sitosterol is plant sterol found in almost all plants. It is one of the main subcomponents of a group of plant sterols known as phytosterols. It is white in colour and waxy in nature. It has a chemical structure that is very similar to cholesterol. High levels of Beta-sitosterol are found in rice bran, wheat germ, corn oils, and soybeans.

The average American diet lacks this component in their diet. Their diet contains only 200 to 300 mg of beta-sitosterol per day, which is not adequate.


The benefits of Beta Sitosterol are as follows: -

Controlling Cholesterol

Beta-sitosterol has been known to reduce cholesterol levels over the last three decades. Its close chemical resemblance to cholesterol enables it to block the absorption of cholesterol by competitive inhibition. Although beta-sitosterol is not well absorbed by the body (5-10%), when consumed with cholesterol it effectively blocks cholesterol's absorption, resulting in lower serum cholesterol levels. Beta-sitosterol has also been shown to improve lipoprotein (HDL, LDL) profiles.

Promoting Prostate Health

In preventing and treating prostrate problems like benign prostatic hyperplasia (BPH), herbs such as saw palmetto extract, Pygeum africanum, and stinging nettle and pumpkin seeds are recommended.

In Europe, herbal preparations were often considered prescription drugs for patients with BPH. Plant sterols actually improved prostate symptom scores and reduced urine volume and residual urine levels without reducing the size of the prostate. Beta-sitosterol was one of the major components in these herbal preparations. Researchers also cited that beta-sitosterol alone was an effective option in the treatment of BPH.

Anti-Cancer Effects

Beta-sitosterol acts against cancer. It is found to reduce the growth of human prostate and colon cancer cells. It also acts against lymphocytic leukemia.

It appears that diets high in vegetables and fruits prevent cancer to a certain degree. Soybeans are superb sources of protein that reduces the risk of cancer too. Beta-sitosterol is one of the key compounds in soybeans that suppress carcinogenosis.

Boosts Immunity

Beta-sitosterol may give a boost to competitive athletes who often suffer from immune suppression and reduced inflammatory response during their intense training periods and competitions.

Beta-sitosterol had been shown not only to boost their immunity but also noted to enhance lymphocyte proliferation and NK-cell activity. This is particularly useful to people who are physically stressed, medically unwell or recovering from illness.

Normalizes Blood Sugar

Beta-sitosterol has been shown to normalize blood sugar and insulin levels in Type II diabetics by stimulating the release of insulin in the presence of non-stimulatory glucose concentrations, and inhibiting glucose-6-phosphatase.

In the liver, the enzyme glucose-6-phosphatase is the primary pathway for conversion of dietary carbohydrates to blood sugar. Glucose-6-phosphatase dephosphorylates glucose-6-phosphate to yield free D-glucose. Free D-glucose passes into the blood, thus elevating blood sugar levels.

Reducing the blood glucose levels by down-regulation of glucose-6-phosphatase helps delay diabetes caused by old age.


Other Benefits of Beta-sitosterol

Beta-sitosterol has the ability to relieve inflammation, heal ulcers, enhance uterine tone and alleviate cramps. It also has anti-viral, anti-bacterial and anti-fungal agents.


Dosage

1. 300 mg up to 5 grams per day for reduction of high blood cholesterol.
2. Between 60 and 130 mg per day for prostatic hyperplasia-related symptoms.
3. 300 mg supplement per day is recommended as dietary health supplements.


Conclusion

Beta-sitosterol is an effective option in the treatment of benign prostatic hypertrophy, lowering cholesterol, increase immunity and reduce inflammation.

Additional reading: Plant Sterol and the Prostate